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We should re-examine eligibility frameworks for GLP-1 therapies, she said
Review available methylation and functional laboratory testing
Making lifestyle adjustments is essential to reinforce the medications effects and address the behavioral aspects of weight management
This paper is thus conclusive in demonstrating that tirzepatide is associated with a risk of worsening of pre-existing DR but protective against developing any new DR or DME
Comprehensive evaluation should include complete thyroid panel (not just TSH), fasting insulin and HOMA-IR for insulin resistance assessment, cortisol testing for adrenal dysfunction, sex hormone panel (testosterone, estrogen, progesterone), sleep study if sleep apnea is suspected, medication review for weight-promoting drugs, and psychological evaluation for eating disorders or food addiction
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