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The dosing figures cited (such as tesamorelin 2 mg daily in trials, or historic pediatric sermorelin dosing) describe what was studied in clinical or research settings, not what any individual should take

Mitochondrial transcription elongation factor TEFM promotes malignant progression of gliomas

2016;98-B(1 Suppl A):10512

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Astronauts experience an extreme example of this when they go to the International Space Station for long periods of time