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Mesoporous silica nanoparticles (MSNs) and organosilica nanoparticles (MONs) are widely studied as carriers for drug delivery due to their high specific surface area and high drug loading capacity [63]
Histamine is the key inflammatory mediator, but other substances are also released by mast cells, including PAF, eicosanoids, prostaglandins, leukotrienes, substance P, and ROS
Topical clindamycin (Cleocin T, Clinda-Derm) and erythromycin (Akne-Mycin, ATS, Erycette, Erygel, Ilotycin) are antibiotics that are also anti-inflammatory drugs and work well against many bacteria
It is prescribed off-label based on clinician judgment and emerging research
