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Unlike retinol, topical peptides such as GHK-Cu may work to upregulate both the breakdown and synthesis of collagen and other intercellular matrix components, thereby increasing collagen turnover [15]

Because the blend is copper-containing (GHK-Cu) and lacks the KPV calming component, particular caution in the research literature attaches to histamine-reactive or highly sensitive skin

The role of BPC-157 in inflammation and healing

Working with fibroblast cultures, they demonstrated that GHK-Cu stimulated collagen synthesis at concentrations beginning between 10 picomolar and 100 picomolar, with peak stimulation at 1 nanomolar

Enrichment of mitochondrial complex I proteins across AML-8 subtypes (n = 162 patients)