For hepatic specification, the study identified a novel small-molecule cocktail, VDF (Vitamin C, Dihexa, and Forskolin), that could effectively substitute for expensive growth factors like BMPs, FGFs, and HGF
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The studies, reported in Circulation: Arrhythmia and Electrophysiology , point to natriuretic peptide oligomers as pro-arrhythmia mediators in the atria and support a causative role for mutant ANP in the pathophysiology of the associated inherited AFib
Notably, BPC 157 may scavenge reactive oxygen species due to its structure: it contains four carboxylic groups, and when they are reactivated (by glutathione or enzymes), the antioxidant activity is very high