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Phase 2 cagrilintide alone ~10.8% body weight reduction at 26 weeks (4.5mg) Phase 2 CagriSema combo ~15.6% body weight reduction at 32 weeks Phase 3 REDEFINE 1 ~22.7% body weight reduction at 68 weeks Phase 2 CagriSema combination trial The Phase 2 trial of CagriSema was published in The Lancet in 2023, and its results attracted immediate attention

By downregulating NF-kB signaling, KPV reduces pro-inflammatory cytokine secretion without the immune suppression associated with corticosteroids or other pharmaceutical anti-inflammatories

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You want a GLP-1 drug for weight loss only, not for Type 2 diabetes or another condition