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For GLP-1s, that typically means a diagnosis of obesity (BMI 30+) or a weight-related comorbidity with a BMI 27+

Clinical studies show that stopping the medication often leads to weight regain

Tirzepatide may cause slightly more headaches initially due to its dual receptor activation affecting both GLP-1 and GIP pathways in the brain simultaneously, though the data does not show a statistically significant difference between the two medications

If a welcome package looks generous, weigh it against the required turnover and time limits