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Patorno E, Htoo PT, Glynn RJ et al (2021) Sodium-glucose cotransporter-2 inhibitors versus glucagon-like peptide-1 receptor agonists and the risk for cardiovascular outcomes in routine care patients with diabetes across categories of cardiovascular disease

469,470 SIRT3 overexpression enhances SOD2 activity, lowering ROS, 471 and suppresses fibrosis pathways such as the TGF-/Smad pathway