For many people, yes but how much depends in large part on what happens after they stop
Studies show that glutathione supplementation increases plasma antioxidant capacity and reduces oxidative stress biomarkers by up to 35%, confirming its role in recycling and regeneration pathways (NIH)
First, since HSL is apparently the primary diacylglycerol lipase in adipose tissue, the accumulation of diacylglycerol in WAT of HSL null mice might interfere with normal adipocyte differentiation or function through the activation of protein kinase C family members and their downstream targets, which are known to affect cell proliferation, apoptosis, and differentiation (Figure 2A)
However, if you notice hardening or worsening swelling that gets worse over weeks, this could be a sign of localized hypersensitivity and/or even a secondary bacterial infection
Both the occluded and the inward-facing structures show Na + coordinated deep within an aqueous cavity that is allosteric to the carnitine-binding site