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Honest caveat: A Phase 2b human trial showed no significant weight loss vs placebo
Moreover, it is very rare that any forms of vitamin B12 are found in plant-based foods, making a dietary supply of B12 difficult for vegans to obtain (see here: Vitamin B12 for Vegetarians and Vegans)
AOD-9604 lacks this broad receptor engagement, confining its research activity to lipolytic pathways, which makes it a more targeted and mechanistically distinct compound for metabolic research models
Studies confirmed that animals lacking these receptors showed no lipolytic response, validating this as the primary pathway
Table of Contents: Can B12 shots interact with any medications
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