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Quick Answer: Semaglutide is not established to directly cause joint pain based on FDA clinical trial data, though some patients report musculoskeletal discomfort that may result from indirect factors such as rapid weight loss or biomechanical changes
As more data comes out, Im feeling more and more comfortable about the safety argument with these medications
doi: 10.1080/01688638908400946 158 BiswalBKunwarPNatelsonBH
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