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While the science behind NNMT inhibition is of genuine research interest, current gray-market distribution means buyers without independent verification cannot be confident in what they receive

It is no longer an antioxidant

Fatigue is listed as a common adverse reaction (occurring in 5% of patients) in the FDA prescribing information for both Wegovy (semaglutide 2.4 mg) and Zepbound (tirzepatide), and occurred more frequently than with placebo in clinical trials

It should be noted that Hims thinks it will be able to keep selling compounded GLP-1s even after shortages end since it personalizes doses and alters drug formulations

10.1016/j.ejphar.2013.08.043 97