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It stimulates the release of growth hormone and has been shown to reduce scaring and cardiac remodeling following myocardial infarction
Additionally, the provider can apply topical numbing cream to the injection area to minimize the discomfort
Over-the-counter antiemetics like meclizine or dimenhydrinate may help for more persistent nausea, though sedation can be an issue
Some patients may achieve adequate glycemic control or weight loss at this dose level, particularly those with mild metabolic dysfunction or those who are particularly sensitive to the medications effects
In the decades since, researchers have repeatedly returned to it as an open question in neurochemistry, with one influential review aptly describing it as a "still unresolved riddle" (Kovalzon et al., 2006)
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