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Priority research needs include large-scale randomized controlled trials to establish efficacy and safety, dose-ranging studies to optimize treatment protocols, long-term safety studies particularly regarding cancer risk, and comparative effectiveness research with established therapies
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Ma XH, Piao SF, Dey S, McAfee Q, Karakousis G, Villanueva J et al
LF, JB, HA, JR, and LS contributed to writing and editing of the draft
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