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Clinical Case 2: You start patient on drug
2017 Feb 21:10:34
10 Within our natural circadian rhythm, increasing melatonin lowers our brain activity and tell our bodies that it is time to sleep
This incretin effect is considerably attenuated in people with type 2 diabetes (see Figure 1), a loss that is even considered an early indicator of the disease, but it was observed that this deficit could be completely corrected by the continuous infusion of GLP-1 to diabetic patients
Neuropharmacology 128, 142151
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