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References Lei Q, Pan XQ, Chang S, Malkowicz SB, Guzzo TJ, Malykhina AP
And Pinealon studies are predominantly preclinical
Mechanisms underlying neuroprotection include enhanced cerebral angiogenesis supporting tissue oxygenation, anti-inflammatory effects reducing secondary injury, antioxidant activity limiting free radical damage, and modulation of neurotransmitter systems including the dopamine/glutamate/NO system
John's Wort is an OTC dietary supplement Bottom line / disclose both agents to your clinician
Sleep improvements are typically the first change patients notice
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