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Safety risks include immune reactions, infections at the injection site, disruptions to metabolism, effects on hormone signalling and cardiac function, and the promotion of tumour growth
doi: 10.1128/mBio.00384-21 83 BozorgmehrNOkoyeIOyegbamiOXuLFontaineACox-KennettNet al
Toxins 11 (7), 374
Of note, the dose is based on the basal insulin component in units
Theoretical frameworks suggest starting tesamorelin at 1mg daily for 2 to 4 weeks before adding retatrutide, then escalating to the standard 2mg daily once tolerance is established
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