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198,199 Downregulated expression of LncRNA Dact3-As1 can promote the proliferation, invasion, and migration of gastric cancer cells, 200 and is associated with poor prognosis in patients
Nevertheless, downstream analyses identified reproducible differences in specific metabolites that were consistently associated with ASD status within this cohort
Recent in vivo measurements of the brain and blood GSH may shed light on GSH changes earlier in the disease
The safest current interpretation is that methylation-related concerns are biologically plausible and relevant to study design, but they are not established as consistent toxicological findings for 5-Amino-1MQ under all published preclinical conditions
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