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Endogenous ligands produced during brain injury activate Toll-like receptor 4 (TLR4), which in turn activates NF-B through the MyD88-dependent signaling pathway, leading to the transcription of numerous pro-inflammatory factors (Brancato et al., 2013)
So some doctors are prescribing it for addiction related purposes but theyre doing it off-label, so it means that the drug itself hasnt been approved for those purposes
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