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As forces through the extracellular matrix are applied, cell deformation through the actin cytoskeleton to the nucleus induces nuclear strain that, in turn, can affect transcription and a host of cell responses, such as inflammation, migration, proliferation, and differentiation 3,4,14,15
Mistake 1: staying at microdoses too long Microdosing is a bridge, not a destination
Its main purpose is to mix the ingredients homogenously
Often, it is best to incorporate all three types since they work with key enzymes together in the body
Still, prediction is only part of the story
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