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[8] Elliott, R
This phenomenon, sometimes called tolerance or tachyphylaxis, is not well-studied specifically for semaglutide, but it is reported frequently in practice
The hearing spawned controversy within the FDA well before it began
That changed after chemist Bruce Merrifield developed solid-phase peptide synthesis, a breakthrough that earned him the Nobel Prize in 1984 and dramatically simplified production of these fragile biomolecules by allowing them to be built much more efficiently compared to purification
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