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Some contraindications (reasons not to take B12 shots) include: Allergies to cyanocobalamin or methylcobalamin Kidney or liver disease Eye issues, especially if you have Lebers disease A current infection If youre taking medication related to bone marrow You should talk to your doctor about the above conditions before getting B12 injections

2025 Sep 3:S1534-5807(25)00530-1

Made from three amino acidscysteine, glutamine, and glycineit plays a crucial role in protecting cells from damage caused by free radicals and toxins

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For autoimmune patients already at risk for bone loss, this could be a clinically meaningful distinction when choosing between available GLP-1/GIP medications