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When these repair mechanisms are successful, misfolded proteins are cleared or refolded, mitochondrial membrane potential is restored, and endoplasmic reticulum stress is alleviated, allowing cells to gradually return to a normal physiological state

17 Subsequent to this, her son with similar features on examination and also carrying the variant had a bowel rupture after a minor insult at the age of 24

Minimal progress adjustments: If showing some improvement but less than hoped, consider increasing dose 25-50% (200mcg to 300mcg BPC-157, 2mg to 3-4mg TB-500)

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More severe skin hyperextensibility is observed in certain types of EDS