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These medications, which include the active ingredients semaglutide (like in Wegovy) and tirzepatide (like in Zepbound and Mounjaro), mimic natural gut hormones
Its available under two brand names
Women of childbearing potential should use effective contraception while taking Wegovy and should discontinue treatment at least 2 months before a planned pregnancy, as semaglutide is not recommended during pregnancy or breastfeeding
NCT04777396, NCT04777409
Triple agonists simultaneously activate three distinct G-protein-coupled receptors: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)
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