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The only randomized controlled trial on GLP-1s and sexual desire used 24 lean healthy men on dulaglutide for four weeks

When evaluating whether semaglutide might be contributing to leg cramps in an individual patient, clinicians must consider the temporal relationship between medication initiation or dose escalation and symptom onset, the presence of alternative explanations, and whether symptoms resolve with dose adjustment or discontinuation

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T., Flavius, M., Rosca, A., Constantin, C., Scurtu, A., Moriczi, R., & Muresan, M

Yucca Health operates in a competitive landscape that includes several other telehealth platforms offering compounded GLP-1 medications