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Weighted UniFrac distance analysis, incorporating phylogenetic and abundance information, confirmed significant dysbiosis in the VPA-ASD model, with the highest dissimilarity from controls (Figure S4E)
4.5 Clinical trials of ferroptosis inhibition therapies for central nervous system diseases Several antiferroptotic therapeutics have advanced to clinical trials, offering hope for treating ferroptosis-related conditions, especially in CNS diseases, where ferroptosis plays a key role in neuronal damage and progression
While we believe the PCAC meeting increases the likelihood of policy changes, those changes are not guaranteed, and new policies could come with limitations
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