tirzepatide for ckd Interplay of Chronic Kidney Disease and the Effects of in Patients With Heart Failure, Preserved Ejection Fraction, and Obesity: The SUMMIT Trial Tirzepatide (Zepbound) showed improved kidney

Starting with a lower dose and gradually increasing it helps minimize these issues

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Efficacy analyses were performed on two sets: the full analysis set, defined as all unique randomized patients grouped according to the treatment assigned at randomization, thereby following the intent-to-treat principle, and an on-treatment analysis, defined as all exposed patients while they were receiving treatment (that is, had received at least one dose in the previous 35 d), grouped according to the treatment that they received