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The expression of the lysosomal enzyme LAL is more pronounced in M2 than in M1 macrophages and is essential for the response and activation of IL-4-induced M2 macrophages (Huang et al., 2014) (Figure 1)
It may also play a role in preventing tissue breakdown, which can occur when restricted blood flow causes tissue damage
In this paper we are mainly interested in intracellular liver metabolism, so we take a somewhat simple view of the fates glutathione and its metabolites in the blood
M., ODwyer, S
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