The most common side effects with topical use include mild redness, temporary stinging at application site, and initial purging (worsened appearance before improvement)
307,308 Additionally, GLP-1R signaling may affect other macrophage functions, such as phagocytosis, migration, and cell survival
Atoms are represented as spheres and are colour-coded: carbon (grey), hydrogen (white), nitrogen (blue), oxygen (red) and sulphur (yellow)
Warning letters issued to companies for unapproved GLP-1 products including GLP3
The 2.5 percentage point gap between male and female weight loss percentages is the smallest gender gap ever recorded in an obesity pharmacotherapy trial