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In an Egyptian study [19], the authors found significant differences between the double present genotype (+/+) and either or both null genotypes of diabetics (P = 0.002 and P = 0.009 respectively) when compared to the control subjects
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In addition to increasing superoxide levels, SOD1 mutations can damage neurons in other ways
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The depletion of glutathione also plays a critical role in the exacerbation of mast cell activation syndrome (MCAS) and dysautonomia, including postural orthostatic tachycardia syndrome (POTS)
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