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Individuals who are pregnant, planning pregnancy, or breastfeeding Patients with a history of certain endocrine or thyroid disorders Those with a history of eating disorders Individuals with uncontrolled gastrointestinal conditions Patients with known sensitivity or adverse reactions to similar medications Anyone unable to commit to ongoing monitoring and follow-up care A consultation helps determine the safest and most appropriate treatment path

(This is, possibly, especially helpful if your diabetes symptoms have not responded well to a GLP-1 receptor agonist alone.) That said, Mounjaro and Trulicity do still have several things in common

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There is no official contraindication to taking tirzepatide and berberine together, though interaction data are limited