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This theme is more hypothesis-generating than definitive, because much of the evidence comes from narrative reviews and ongoing trials rather than completed comparative outcome studies

Current data suggests that stopping semaglutide at least two months before attempting conception may reduce theoretical risks, though robust fertility studies remain limited

Especially in the beginning, but also when you titrate up to the next dose that depression can really worsen

Nucleic Acids Res 43, D345D356, doi: 10.1093/nar/gku1214 (2015)

Posterior capsule opacification in rabbit eyes implanted with 1-piece and 3-piece hydrophobic acrylic intraocular lenses