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Higashi Y, Sukhanov S, Anwar A, Shai SY, Delafontaine P: IGF-1, oxidative stress and atheroprotection
Key findings included: Greater reductions in body weight (measured by percent body mass index change and excess weight loss) Improved eating behaviors No differences in safety outcomes, including emergency department visits, readmissions, reoperations, or gastrointestinal side effects
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Method Development Tips Method development often begins with small pilot plates before larger screening panels
Calcineurin inhibits Na+/Ca2+ exchange in phenylephrine-treated hypertrophic cardiomyocytes
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