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49 Traditional small-molecule antioxidants have failed to alleviate oxidative stress in vivo because of poor brain compatibility, high dosage requirements, and high reactivity, limiting their clinical use

secondary outcomes included new-onset MACE (heart failure, myocardial infarction, stroke) (Table 1) Results: The matched analysis included 2,698 patients per group (Table 2)

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12 weeks (1x daily, 5-on/2-off) 4 vials 60 doses needed (5x12)