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Forty-eight hours post-transfection, cells were detached and washed with and re-suspended in HBSS
Abstract Glucagon-like peptide-1 (GLP-1) is a gut-derived hormone essential for maintaining glucose homeostasis through multiple physiological pathways: triggering insulin release, inhibiting glucagon secretion, delaying gastric emptying, enhancing feelings of fullness, and suppressing appetite
doi:10.1111/j.1528-1167.2005.00605.x
Native IGF-1 added to cell culture media at the start of a 72-hour experiment will be substantially degraded and sequestered by the end of that window, even in serum-free conditions
Oral GLP1s are a highpriority class for metabolic disease (obesity, type 2 diabetes) and Hengruis move signals Chinas accelerating push to develop homegrown oral GLP1 therapies amid global competition and mixed results from some multinational programs
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