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Neurological research: Emerging work points to neuroprotective and neuroregenerative properties: protection against various neurological insults, better nerve regrowth after injury, possible benefits for traumatic brain injury recovery, and potential applications in neurodegenerative disease research

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347,348 High glucose levels inhibit the PI3K/Akt pathway in Schwann cells, leading to overexpression of DNA methyltransferases (DNMT1 and DNMT3a) and upregulation of thioredoxin-interacting protein (TXNIP)