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The secondary endpoint included changes in glucose, insulin, HOMA-IR, blood pressure, lipid profiles, uric acid, free fatty acids, hepatic profile, and the sensation of fatigue and hunger

The JAK-STAT3 signaling pathway not only has a crucial role in the regulation of innate and adaptive immunity but in non-immune cells, it can control cell proliferation, metabolism, and cellular senescence in a context-dependent manner (see below)

3 (download XLSX Spatial bregma and dataset mapping source data

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The electrode was gently inserted into direct contact with the hydrogel, and readings were recorded after a 1-minute stabilization period to ensure accuracy