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Sources: Astrup A, et al

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Peptide chemistry does not allow this safely

Human Evidence Clinical human data for GHK-Cu specifically remains limited but growing

Similar to the binding pattern between c-MET I-SEMA and HGF I-K3, the loop of c-MET (residues 300311) that undergoes proteolytic cleavage during maturation also contributes to the binding between c-MET II-SEMA and HGF I-K1