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The literature also describes upregulation of growth factors involved in tissue repair, modulation of nitric oxide synthase activity, and effects on the dopaminergic and serotonergic systems that are harder to interpret clinically [Sikiric et al., Inflammopharmacology, 2018]
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At a concentration of 10 M, morroniside showed a more powerful effect on ORSCs proliferation compared with the control group or with the group treated with 1 M morroniside
Endothelial senescence (2025, PMC) Reported FOXO4-DRI clearing senescent endothelial cells via a p53/BCL-2/caspase-3 pathway in animal and cell models
The body may need additional support during periods of increased stress, exposure to environmental toxins, or as a natural response to aging
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