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Conclusions GLP-1RAs are effective at improving glycaemic control and, by virtue of their mechanism of action, have a low risk of hypoglycaemia combined with the potential for weight loss

Contributes to better sleep quality

He stopped taking the drug after a few months

A recent meta-regression analysis of GLP-1R agonist cardiovascular outcome trials ( LEADER, SUSTAIN-6, EXSCEL, HARMONY, REWIND , and PIONEER-6 trials ) has suggested that clinicians should consider the status of diabetic retinopathy in patients before initiating treatment with GLP-1R agonists (Bethel et al., 2021)

Both compounds show significantly better GI tolerability than Semaglutide, which causes nausea in 44% of users and vomiting in 24%