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This study aimed to compare the physiological roles of GIPR in the AP and hypothalamus by targeted regional KO of Gipr , using a floxed Gipr mouse model (Gipr fx/fx ) stereotactically injected with adeno-associated virus (AAV) encoding Cre-recombinase to generate mice with KO of Gipr in either the AP (Gipr AP-KO ) or hypothalamus (Gipr hypo-KO )
While widely available through peptide vendors, it does not carry the manufacturing standards, safety testing, or oversight of approved medications or supplements
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