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Measurable weight loss often begins within the first 2-4 weeks, with more consistent results appearing in months two and three as the dosage is optimized
In vitro studies suggest that this effect is mediated by brown adipose tissue (BAT) [61]
Whilst all GLP-1 receptor agonists bind to the same receptor, subtle differences in binding affinity, receptor residence time, and downstream signalling may affect the intensity of gastrointestinal effects
PMID: 30939721
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