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& Sansom, M

This is distinct from hypertrophy, which is the growth of existing cells

The most popular method to administer GH treatment is through subcutaneous injections

In both male and female GHRKO mice, disruption of the GH/IGF-1 axis from birth results in mice that are remarkably long lived, but temporal disruption of this pathway in young adults (aGHRKO mice) improves lifespan only in females 17 , an observation which is consistent with the beneficial effects of targeting IGF-1R signaling post-development on female healthspan and aging in this study

A 2001 editorial in the European Journal of Anaesthesiology described DSIP as "incredibly safe," noting that no dose had ever killed an animal subject in research, and the only human side effects observed were transient headache, nausea, and vertigo