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To investigate the effects of 2DG on metabolism and the inflammatory response within the CNS, we utilized two complementary models of LPS-induced neuroinflammation, delivering LPS either systemically through intraperitoneal (ip) injection or directly into the CNS via intracerebroventricular (icv) administration
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It is a poorer fit, or warrants caution, in patients with known sulfur or sulfite sensitivity, in poorly controlled asthma, and in anyone whose expectations are anchored to unproven claims particularly cosmetic skin-lightening
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