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In addition, NLRP3 achieves dynamic binding to the Golgi apparatus at Cys130 through a palmitoylation cycle, and the dynamic balance between palmitoylation (catalyzed by ZDHHC3/7) and depalmitoylation (mediated by APT2) regulates the residence time of NLRP3 at the membrane (72)
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[19]S.M
Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors
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