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Another significant metformin side effect: vitamin B12 deficiency
Hydroxocobalamin regimen (UK example): 1 mg (1000 g) IM three times a week for 2 weeks (loading), then 1 mg every 3 months thereafter
When to Use Each Form of Vitamin B Supplementation Oral capsules work well for most adults with adequate stomach acid and intrinsic factor, especially when taking 1,0002,000 g daily
Some people achieve their weight loss goals with injectable tirzepatide and want to switch to oral for maintenance convenience
J.et al (2000)
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