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Recent studies have demonstrated differential expression patterns of Fetuin-A in neurological disorders such as PD, amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS) [129,130,131]
Briefly, to verify the targeted binding between miR-29b-3p and the GGCT gene, a 2000-bp DNA fragment (derived from the transcription start site of the GGCT gene) was inserted into the pmir-GLO-Basic vector to construct the wild-type pmir-GLO-GGCT-3 UTR reporter plasmid (wt) and the mutant pmir-GLO-GGCT-3 UTR reporter plasmid (mut)
It can be recycled back to methionine through remethylation or irreversibly directed into transsulfuration to produce cysteine and downstream sulfur compounds
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Long F, Liu W, Jia P, Wang H, Jiang G, Wang T
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