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Validation studies of local environmental changes in Ca 2+ and pH within astrocytes in the hippocampus of animals with epilepsy revealed that all cellular enzyme responses are affected by Ca 2+ and pH and that controlling astrocyte pH and/or Ca 2+ may be a new target for epilepsy therapy or the prevention of epilepsy-related adverse events (61)
Following endogenous growth hormone release, insulin-like growth factor-1 (IGF-1) mediates many downstream physiological processes involved in normal growth hormone biology
Ito T, Schaffer SW, Azuma J
Cui S, Ghai A, Deng Y, Li S, Zhang R, Egbulefu C
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