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Similarly, tirzepatide, a dual GLP-1R and GIP receptor agonist, does not seem to cross the BBB efficiently (Rhea et al., 2024)
Highlighting fewer patients achieving similar results with other treatments underscores semaglutides superior efficacy
[1] [5] Research into transdermal delivery of peptide medications faces significant challenges due to the large molecular size of GLP-1 analogs and the skin's natural barrier function
Key Takeaways RUO labeling alone is not sufficient to protect the sale of GLP-1 compounds
For example, the medication itself could cause issues that impact your metabolism
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