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It must be swallowed as a whole
This dual action on both glucose metabolism and appetite has made GLP-1 a therapeutic target for type 2 diabetes and obesity management
Phase Dual escalation 3 Weeks 21-24 Tirzepatide 12.5 mg/week Cagrilintide 1.7 mg/week Notes Approach maintenance
Novo Nordisk (2018)
GLP-1 is a 30-amino acid peptide secreted by intestinal L-cells in response to food intake, released from pro-glucagon by the action of pro-hormone convertase, which processes preproglucagon, the precursor of several glucagon-related peptides
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